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ISBN-10: 0929600932

ISBN-13: 9780929600932

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Extra info for Development of a Biokinetic Model for Radionuclide-Contaminated Wounds and Procedures for Their Assessment, Dosimetry and Treatment

Example text

7. 2). 227Ac3+ in rats 44 / 4. GENERIC BIOKINETIC MODEL described by interaction between the soluble and CIS compartments, but the PABS compartment comes into play in predicting long-term retention for ~2 % of the deposited actinium. Although this latter quantity persists beyond the range of the data, it is within the bounds of the default parameters for the stronglyretained category, of which it is a member. 017 Pg), there was no reason to invoke immobilization in the TPA compartment. Therefore, the transfer rate from PABS to TPA was set to zero.

Wounds suffered included burns, lacerations, broken bones, internal injuries, and retained fragments, some of which were DU. In addition to embedded fragments and wound contamination, personnel in or on these vehicles also had the potential for inhaling the DU particulates and aerosols generated during the penetration. Personnel entering a vehicle after it was struck by a DU penetrator could also have inhaled DU particulates. Standard surgical criteria were used to determine whether embedded fragments should be removed, including the possibility of surgical damage to adjacent structures.

By the second to third week of healing, the wound contracts by collagen remodeling and a scar is completed (Singer and Clark, 1999). 4 Burns Healing of burns differs somewhat from that of mechanical injuries, and it depends on the degree of damage (first-, second- or third-degree burn). The most important characteristic of a burn is the depth of damage. This affects the amount of necrosis, capillary destruction (the microcirculation is key to burn recovery), edema, and inflammation, and how much tissue must be repaired.

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